Like other well-known GLP-1 drugs—such as Wegovy®, Tirzepatide (Compounded Mounjaro)is a once-weekly injectable medication that helps regulate blood sugar levels. Currently, it is indicated for use in patients with type 2 diabetes, but it has surpassed all trials and studies as a weight-loss drug and is prescribed off label for the reasons of use for weight loss.

Clinical trials found doses of tirzepatide effective in reducing hemaglobin A1C levels and assisting with weight loss. Early data suggests that it may even reduce the likelihood of cardiovascular events such as heart attack or stroke, though a trial tackling this question has not yet concluded.

As with all of MedShape Weight Loss Clinic Programs, Tirzepatide is meant to be used alongside lifestyle changes, i.e. changes to food, sleep, and exercise. It is expected that the drug will work best when accompanied by coaching and support from MedShape’s trained professionals.

The recommended starting dosage of Tirzepatide (Generic Mounjaro)  is 2.5 mg. After 4 weeks, doses may be increased in 2.5 mg increments, as tolerated, up to a maximum of 15 mg once weekly. Doses are set and monitored by a MedShape healthcare provider and may be adjusted to help patients meet their blood sugar, weight loss, and metabolic health goals.

How Does Tirzepatide (Compounded Mounjaro) Work? Buy mounjaro online

Tirzepatide (Compounded Mounjaro) works similarly to the other drugs in the GLP-1 family, but it contains an extra molecule that may give it a slight edge.

The medication has a dual-action design, mimicking the action of not one but two incretin hormones involved in blood sugar control: Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). This unique dual action makes it the first-in-class medicine that acts on both of these receptors.

According to a press release published by Eli Lilly, “GIP is a hormone that may complement the effects of GLP-1 receptor agonists. In preclinical models, GIP has been shown to decrease food intake and increase energy expenditure, therefore, resulting in weight reductions, and when combined with GLP-1 receptor agonism, may result in greater effects on markers of metabolic dysregulation such as body weight, glucose, and lipids.”

Incretin hormones are released whenever food is consumed. Among other things, they help promote a feeling of fullness by delaying gastric emptying and activating the satiety centers of the brain. They also boost insulin production in the pancreas, and suppress glucagon production, both of which help normalize blood sugar. All of this happens in a glucose-dependent manner, which means incretin hormones—or their imitators, i.e. GLP-1 and GIP receptor agonists—are unlikely to cause severe hypoglycemia.

What about your natural incretin hormones? Studies have found that people with overweight or obesity may have a reduction in incretin effects, particularly if they have had frequent weight fluctuations due to yo-yo dieting. GLP-1 medication narrows the gap, making it easier to reach your goals and lower your metabolic set point.

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• MOUNJARO is an injectable prescription medicine that is used along with diet and exercise to improve blood sugar (glucose) in adults with type 2 diabetes mellitus.

• It is not known if MOUNJARO can be used in people who have had pancreatitis.

• MOUNJARO is not for use in people with type 1 diabetes.

• It is not known if MOUNJARO is safe and effective for use in children under 18 years of age. Do not use MOUNJARO if:

• you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

• you have had a serious allergic reaction to tirzepatide or any of the ingredients in MOUNJARO. See the end of this Medication Guide for a complete list of ingredients in MOUNJARO. Before using MOUNJARO, tell your healthcare provider about all of your medical conditions, including if you:

• have or have had problems with your pancreas or kidneys.

• have severe problems with your stomach, such as slowed emptying of your stomach (gastroparesis) or problems with digesting food.

• have a history of diabetic retinopathy.

• are pregnant or plan to become pregnant. It is not known if MOUNJARO will harm your unborn baby. Tell your healthcare provider if you become pregnant while using MOUNJARO.Buy mounjaro online