TRESIBA
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Tresiba Flextouch from the Novo Nordisk manufacturer is a diabetes medicine with insulin degludec (one of the most long-acting basal type basal insulin) active substance to control blood glucose levels. The composition of the drug also includes glycerol – 19.6 mg, phenol – 1.5 mg, metacresol – 1.72 mg, zinc – 32.7 μg (in the form of zinc acetate – 109.7 μg), hydrochloric acid/sodium hydroxide (for pH correction), water – up to 1 ml.
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Insulin degludec is a long-acting basal human insulin analog for subcutaneous injection produced by a process that includes expression of recombinant DNA in Saccharomyces cerevisiae followed by chemical modification. Insulin degludec differs from human insulin in that the amino acid threonine in position B30 has been omitted and a side-chain consisting of glutamic acid and a C16 fatty acid has been attached (chemical name: LysB29(Nε-hexadecandioyl-γ-Glu) des(B30) human insulin). Tresiba is a long-acting human insulin analog indicated to improve glycemic control in patients 1 year of age and older with diabetes mellitus. Buy Tresiba Online
DOSAGE FORMS AND STRENGTHS
TRESIBA is available as a clear, and colorless solution for injection in:
• 100 units/mL (U-100): 3 mL FlexTouch disposable prefilled pen
• 200 units/mL (U-200): 3 mL FlexTouch disposable prefilled pen
TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) works by enhancing the body tissues to rapidly uptake glucose from the blood which results in controlled blood glucose level thus treating diabetes mellitus and its associated symptoms in affected individuals.
DIRECTIONS FOR USE Buy Tresiba Online
Administer TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) as advised by your physician. It is given under the skin (subcutaneously) at specific areas such as front of the thighs, upper arms, or the front of the waist (abdomen). Keep changing the site of injection each day to reduce the risk of developing lumps and skin pitting. Insert the needle into the skin as per your doctor’s advice. Ensure that you can see the dose counter properly. Gently press and hold down the dose button until the dose counter value returns to zero. Leave the needle under the skin for minimum 6 seconds. Pull out the pen straight up from the skin. If blood oozes out at the injection site, press gently with a cotton swab. Do not rub the bleeding area. Always dispose of the used needles in the appropriate sharp’s container to reduce the risk of infection, contamination, insulin leakage, blocked needle issues, and inaccurate dosing. Your doctor will decide the correct dose and duration for you depending upon your age, body weight, stress, physical activity, and disease condition.
SIDE EFFECTS OF TRESIBA 100IU FLEX TOUCH PEN(PREFILLED)
COMMON Buy Tresiba Online
- Injection site reactions such as pain, redness, itchy welts, swelling, and/or itching
- Signs of low blood sugar level such as sweating, tiredness, dizziness, increased hunger, and/or tingling lips
UNCOMMON
- Swelling around your joints
RARE
- Signs of allergic reactions such as itchy welts, swelling of the tongue and lips
- Diarrhoea, nausea
- Tiredness
- Itching
Stop taking TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) and contact your doctor if you experience any of the following side effects:
- Signs of serious hypoglycaemia (condition marked by very low blood sugar levels) such as looking pale (pallor), shakiness, dizziness/lightheadedness, sweating, and/or nausea
- Signs of a serious allergic reaction such as local reactions (redness, itching, and rashes) spreading to other parts of your body, sudden feel of being unwell with sweating, vomiting, difficulty in breathing, rapid heartbeat, and/or dizziness
- Signs of heart failure such as unusual shortness of breath, rapid increase in weight, and/or localized swelling (oedema)
- Serious injection site reactions such as pain, redness, hives (red itchy skin), swelling, and itching
- Signs of ketoacidosis (serious complication of diabetes) such as flushing, dryness of skin, sleepiness, tiredness, dry mouth, fruity breath, increased frequency of urination, increased thirst, loss of appetite, nausea, and/or vomiting
HOW TO MANAGE SIDE EFFECTS Buy Tresiba Online
Serious hypoglycaemia (very low blood sugar):
Try to have high sugar snack (such as sweets, biscuits or fruit juice). Measure your blood sugar if possible and take rest. Wait until the signs of too low blood sugar disappears or when your blood sugar level has settled. Buy Tresiba Online
Diarrhoea:
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to treat diarrhea. Consult and inform your doctor if the symptom worsens.
Nausea:
Take TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) with/just after a meal. Stick to simple meals. Avoid eating oil rich/spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, and drink slowly in between meals. Consult your doctor if the condition worsens.
Tiredness:
Make sure you take rest and drink plenty of fluids. Avoid or limit the consumption of alcohol. Try to take TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) at a time when you can sit down (or lie down) when the symptoms are at their worst. Avoid driving or using tools or machinery until you feel well.
Itchy Skin:
Try to pat or tap your skin instead of scratching it. Hold a damp towel to cool your skin. Wear loose clothing and avoid tight clothes, or clothes made from wool or synthetic fabrics. Avoid using perfumed soaps, deodorants or moisturizers and use a skin softener regularly.Buy Tresiba Online
WARNING & PRECAUTIONS Buy Tresiba Online
PREGNANCY
TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) should be used with caution during pregnancy and in women planning to become pregnant. Consult your doctor before administering the medicine.
TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) should be used with caution in breastfeeding women. Consult your doctor before administering the medicine.
DRIVING AND USING MACHINES
Do not drive or operate machines if you experience symptoms associated with too low blood sugar (such as shaking, sweating, nervousness) or high blood sugar (such as increased thirst, tiredness, blurred vision) after administering TRESIBA 100IU FLEX TOUCH PEN(PREFILLED).
ALCOHOL
Avoid consumption of alcohol while administering TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) since it may cause too low blood sugar.
KIDNEY
TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) should be used with caution in patients with kidney problems. Consult your doctor before administering TRESIBA 100IU FLEX TOUCH PEN(PREFILLED).
LIVER
TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) should be used with caution in patients with liver problems. Consult your doctor before administering TRESIBA 100IU FLEX TOUCH PEN(PREFILLED).
ALLERGY
Do not use TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) if you are allergic to Insulin degludec, and/or any other ingredients of this medicine.
OTHERS
Before taking TRESIBA 100IU FLEX TOUCH PEN(PREFILLED), inform your doctor if you:
- Have too low/high blood sugar
- Have eye disorders/poor eyesight
Use in Paediatrics:
TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) should be used with caution in in children and adolescents (aged 1 to 18 years). Consult your doctor before administering the medicine to the child.
Use in Geriatrics:
TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) should be used with caution in elderly patients (aged 65 years and above). Consult your doctor administering the medicine.
INTERACTIONS
A. Drug-Drug Interactions:
Before using TRESIBA 100IU FLEX TOUCH PEN(PREFILLED), inform your doctor, if you are taking any of the following medicine:
- Other medicines for diabetes such as oral diabetic medicines (Ex. pioglitazone, metformin), injectable diabetic medicine (Ex. insulin lispro)
- Sulphonamides (medicines used to treat infections) Ex. sulfadiazine, sulfamethizole
- Anabolic steroids (medicines used to treat deficiency or malfunction of sex hormones) such as testosterone
- Beta-blockers (medicines used to treat high blood pressure) Ex. Metoprolol
- Salicylates (medicines used to treat pain and mild fever) Ex. acetylsalicylic acid or aspirin
- Monoamine oxidase (MAO) inhibitors (medicines used to treat depression) Ex. isocarboxazid
- Angiotensin converting enzyme (ACE) inhibitors (medicines used to treat some heart problems or high blood pressure) Ex. enalapril
- Medicine used to treat endometriosis Ex. danazol
- Medicines used to contraception such as oral contraceptives Ex. desogestrel, ethinyl estradiol
- Medicines used to treat thyroid problems Ex. thyroid hormones
- Medicines used to treat for growth hormone deficiency Ex. growth hormone,
- Medicines used to treat inflammation such as glucocorticoids Ex. cortisone
- Sympathomimetics (medicines used to stimulate sympathetic nervous system) Ex. epinephrine/adrenaline, salbutamol, terbutaline
- Thiazides (medicines used to treat the high blood pressure high blood pressure or water retention in the body) Ex. chlorothiazide
- Medicines used to treat acromegaly (excess production of growth hormone) Ex. octreotide, lanreotide
Overdosage:
If you or anyone else accidentally administers too much of TRESIBA 100IU FLEX TOUCH PEN(PREFILLED), consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are low blood sugar associated with symptoms such as sweating, tiredness, dizziness, increased hunger, and/or tingling lips.
SYNOPSIS
| Drug | : | Insulin Degludec |
| Pharmacological Category | : | Antidiabetics |
| Therapeutic Indication | : | Diabetes mellitus type 1 & 2 |
| Dosage Forms | : | Cartridge, Injection |
MORE INFORMATION Buy Tresiba Online
- Keep TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) out of reach in children
- Store TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) in a refrigerator at 2-8°C
FAQs ABOUT TRESIBA 100IU FLEX TOUCH PEN(PREFILLED)
Q. What TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) is used for?
A. TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) is used to treat diabetes mellitus (high blood sugar) in adults, adolescents and children (aged 1 year and above). It is also used in combination with oral/other injectable antidiabetic medicines to treat type-2 diabetes mellitus. The medicine is also indicated for use to treat type 1 diabetes mellitus when used in combination with meal-related rapid-acting insulin medicines in affected individuals.
Q. What happens if TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) is administered more than its required dose?
A. If you or anyone else accidentally administers too much of TRESIBA 100IU FLEX TOUCH PEN(PREFILLED), consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are low blood sugar associated with symptoms such as sweating, tiredness, dizziness, increased hunger, and/or tingling lips.
Q. What are the side effects seen associated with the use of TRESIBA 100IU FLEX TOUCH PEN(PREFILLED)?
A. The most common side effects associated with the use of TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) are low blood sugar levels (associated with symptoms such as sweating, tiredness, dizziness, and/or feeling increased hunger), and injection site reaction (such as pain, redness, itchy welts, swelling, and/or itching). Consult your doctor if any of these symptoms worsen.
Q. How TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) works?
A. TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) helps in lowering blood glucose levels where Insulin Degludec works by enhancing the body tissues to rapidly uptake glucose from the blood which results in controlled blood glucose level treating diabetes mellitus and its associated symptoms in affected individuals.
Q. Can TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) be administered in pregnant women?
A. Yes, TRESIBA 100IU FLEX TOUCH PEN(PREFILLED) can be administered but with caution during pregnancy and in women planning for pregnancy. Consult your doctor before administering the medicine.Buy Tresiba Online
| TRESIBA | Vial (1 x 10-mL vial ), U-100 (5 x 3-mL pen), U-200 (3 x 3-mL pen) |
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